Baltimore, MD is a vivid, distinct city which is Maryland's largest city and commercial hub. It is widely known for awe-inspiring harbour; eccentric, diverse neighborhoods; extraordinary museums; and iconic Johns Hopkins Hospital to the east and the University of Maryland Medical Center. Baltimore settled in the early 17th century and was named after Lord Baltimore (Cecilius Calvert) in the Irish House of Lords. Baltimore's waterfront made it a focal point for tobacco trade with England in its earliest days. By the 18th century, Baltimore had become a storehouse for sugar producing colonies in the Caribbean. Today, Baltimore's waterfront is encompassed by shops, restaurants and other points of interest that draw in tourists and locals. As a major marine and commerce community, Baltimore played a significant role in events that molded our nation's history, including the American Revolution, the Revolutionary War, the War of 1812 and the Battle of Baltimore. Be sure to visit the National Monument and Historic Shrine at Fort McHenry. This is where troops successfully defended Baltimore's cherished harbor. Tragedy struck Baltimore in 1904 when fire depleted most downtown, destroying over 1,500 building in less than 30 hours. With hundreds of established districts, Baltimore is commonly referred to as "Charm City." The likes of writers Edgar Allan Poe and H.L. Mencken, musician James Hubert "Eubie" Blake, and singer Billie Holiday each called Baltimore "home."